The mission of the Center for Genomics & Systems Biology is to define how regulatory networks operate and how they have evolved to generate diversity across species. For this work, we use approaches that span systems biology, comparative functional genomics & bioinformatic analysis focusing on model organisms and phylogenetically related species. The research involves the combined skills of genomicists, bioinformaticians, systematists, and evolutionary biologists all working together. The genomics and bioinformatics faculty in our center are engaged in collaborative projects with scientists at NYU's Courant Institute of Mathematical Sciences, other scientific institutions in the greater New York City area, including The American Museum of Natural History (AMNH), The New York Botanical Garden (NYBG), and the Cold Spring Harbor Laboratories (CSHL), as well as collaborators from around the world. The unique intellectual synergisms brought about by this collaborative genomic consortium group, enables us to develop unique approaches to address questions of comparative functional genomics.